Corrigendum: Fluorescence-tunable Ag-DNA biosensor with tailored cytotoxicity for live-cell applications

نویسندگان

  • Nelli Bossert
  • Donny de Bruin
  • Maria Götz
  • Dirk Bouwmeester
  • Doris Heinrich
چکیده

In the 'Introduction' and 'Results and Discussion' sections of this manuscript, the authors used 2 sequences that were previously published and cited already as references 35 and 44. To better reflect the use of these sequences within the Introduction: " Using these dependencies, we designed Ag-DNA templates to function as an optical sensor in living cells' interior environments (Fig. 1b–d) (for DNA sequences please see Table S1) ". Now reads: " Using these dependencies, we selected and optimized Ag-DNA templates to function as an optical sensor in living cells' interior environments (Fig. 1b–d) (for DNA sequences please see Table S1) ". In the Results and Discussion section under the ' Ag-DNA nanoagent design' subheading: " The design of DNA sequences is the result of optimizing fluorescence and/or sensor properties of Ag-DNA within the cell by varying the base sequences for enhanced performance ". Now reads: " The choice of DNA sequences is the result of optimizing fluorescence and/or sensor properties of Ag-DNA within the cell by varying the base sequences for enhanced performance ". Secondly, " The DNA template, consisting of 28 single bases, is designed to yield an Ag-DNA construct (Ag-28b in Fig. 1b) with strong and stable fluorescence properties upon insertion into living cells ". Now reads: " The DNA template, consisting of 28 single bases, yields an Ag-DNA construct (Ag-28b in Fig. 1b) with strong and stable fluorescence properties 35 , which we show are retained upon insertion into living cells ". In addition, " Here, we demonstrate that by a simple modification of Ag-28b, we produced an Ag-DNA construct which shows optical sensor functionality inside living cells: shortening the 28b sequence by nine bases produces the Ag-19b construct (Fig. 1c), which exhibits an optical response to the intracellular environment " .

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عنوان ژورنال:

دوره 7  شماره 

صفحات  -

تاریخ انتشار 2017